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    Connectome

    Page 40
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      Index

      Page numbers in italics refer to illustrations.

      Abstract ideas, [>]

      Action potentials (“spikes”), [>]–[>]. See also Spikes and spiking

      Adaptation of cortical areas. See Remapping of cortex

      Aging, efforts to suspend, [>]. See also Cryonics; Plastination; “Uploading”

      AIDS, [>]–[>]

      Alcoholics Anonymous, Serenity Prayer of, [>], [>]

      Alcor Life Extension Foundation, [>]–[>], [>], [>], [>]

      promises of, [>]

      and transhumanism, [>]

      uncertainties over, [>], [>], [>], [>], [>]

      Ali, Muhammad, [>]

      Allen, Woody, on immortality, [>]

      Allocortex, [>]

      Alzheimer’s disease (AD), [>], [>], [>], [>]

      mouse models of, [>]

      Amblyopia, [>]–[>], [>]

      Amino acids, [>]

      Amnesiacs, denial by, [>]

      Amputation, and phantom limbs, [>], [>]–[>], [>]

      Aniston, Jennifer, as perception example, [>], [>]–[>], [>], [>], [>], [>], [>], [>], [>], [>]

      Antibiotics, [>], [>]

      Antidepressants, [>], [>]–[>], [>]–[>]

      Antipsychotics, [>], [>]–[>], [>], [>]

      Antonini, Antonella, [>]–[>], [>]

      Aphasia, [>]

      Broca’s, [>], [>]

      conduction, [>], [>]

      Wernicke’s, [>], [>]

      Aplysia californica, [>]–[>]

      Apple Incorporated, modern miracles from, [>]

      Archaeological metaphor for neuroanatomy, [>]–[>]

      Arcuate fasciculus, [>], [>], [>], [>]

      Ariadne, [>], [>]

      Aristotle, on memory, [>]–[>]

      and associationism, [>]

      Artificial intelligence, [>]–[>]

      evaluation of, [>]–[>]

      limitation of, [>], [>]

      Ascaris lumbricoides, [>]

      Asperger’s syndrome, [>]

      ASPM, [>]

      Association(s), [>], [>]

      learning of, [>]–[>]

      sequential rule of, [>], [>]

      simultaneous rule of, [>]

      and sparse connectivity, [>]–[>]

      Associationism, [>], [>]

      ATUM (automated tape-collecting ultramicrotome), [>]–[>], [>], [>]

      “Augmenting Human Intellect” (Engelbart), [>]

      Autism, [>], [>], [>]–[>], [>], [>], [>]–[>]

      attempt to study in animals, [>]

      cause of (genetic vs. environmental), [>]–[>], [>]

      as connectopathy, [>], [>]

      drugs for (and miswiring in animal models), [>]

      genetics of, [>]

      genetic tests for, [>]

      and genomics, [>], [>]–[>]

      and ion channels, [>]

      lack of neuropathology in, [>], [>], [>]

      multiple forms of, [>]

      Autism spectrum disorders, [>]

      Axons, [>]–[>], [>]–[>]

      cross-sections of, [>]

      in dead brains, [>]

      as divergent, [>]

      growth of after birth, [>]

      myelinated, [>]

      and spiking, [>] (see also Spikes and spiking)

      white matter as, [>]–[>]

      mapping of, [>], [>]–[>]

      and wiring of brain, [>]

      Bacon, Francis, [>]

      Bailey, Percival, [>]

      Balanced population, [>]

      “Ball and stick” models, [>], [>]

      Barry, Susan, [>]

      Basal ganglia, [>]

      Baudelaire, Charles, [>]

      Behavior Genetics, Laws of, [>], [>]

      Bernal, J. D., [>]–[>]

      Bicêtre hospital, [>]–[>]

      Binding site, [>]

      “Biologics,” [>]

      Biomolecules, and drug therapy, [>]

      Bipolar disorder, [>]

      Birds, [>]

      similarities of to humans, [>]

      songs of, [>]–[>]

      examination of to find synaptic chains, [>]–[>], [>]

      “Blank slate” view of mind, [>]

      Blue Brain (computer simulation), [>]–[>], [>]–[>], [>]

      Blue Gene/L (computer), [>]

      Blum, Joseph, [>]

      Bock, Davi, [>]

      BOLD (blood oxygen level dependent) signal, [>]

      Bonin, Gerhardt von, [>]

      Boundary detection, [>]–[>], [>]

      Bragg, Lawrence, [>]

      Braille readers, [>]

      Brain(s)

      abnormalities in

      lissencephaly, [>]–[>], [>]

      microcephaly, [>], [>]

      adult plasticity of, [>]

      “areas” and “regions’ of, [>]

      change in (and learning new behavior), [>]–[>]

      complexity of, [>], [>]

      death of, [>]–[>]

      as connectome destruction, [>]–[>]

      development of, [>]

      and abnormalities, [>], [>], [>]

      change easiest in early stages of, [>]

      and gene therapy, [>]–[>]

      and organizational patterns, [>]–[>]

      synapse creation and destruction, [>]–[>], [>]

      enhancing normal function of, [>]

      fMRI in mapping of, [>]–[>]

      forest metaphor for, [>], [>]

      complexity of, [>]

      hierarchical perceptron model for, [>]

      individual differences in functioning of, [>], [>], [>], [>]

      as irreplaceable, [>]–[>]

      Labyrinth metaphor for, [>]–[>]

      left vs. right, [>]

      and hemispherectomy in children, [>]

      and sides of body, [>]

      MRI cross-section of, [>]

      muscles compared with, [>]–[>]

      as mysterious, [>]

      and neuroanatomy, [>]–[>]

      and neurons (see also Neurons)

      and connections between, [>]

      number of, [>]

      organization of, [>], [>]

      plastination of, [>]–[>]

      in recovery from stroke, [>]–[>]

      regions of studied, [>]

      rewiring of, [>], [>]–[>], [>], [>] (see also Rewiring of brain)

      size of

      and autism, [>]–[>]

      and intelligence, [>]–[>]

      measurement of, [>]–[>]

      and mental differences, [>], [>]

      and schizophrenia, [>]–[>]

      structure of, [>]–[>], [>], [>]

      and connectionism, [>]–[>]

      and different levels of activation, [>]–[>]

      vs. function as criterion for division, [>]

      and genius, [>]–[>]

      and individual differences, [>], [>], [>]

      and localizationism, [>]–[>] (see also Localizationism)

      measurement in study of, [>]

      and neuron types, [>], [>]–[>], [>]

      proper division of, [>]–[>], [>]–[>]

      similar functions within region of, [>]

      and specific abilities, [>]

      study of

      as available approach to understanding, [>]

      and regions, [>]

      of Tan, [>]

      and technologies, [>] (see also Technological innovation)

      and thinking, [>] (see also Thought)

      transfer of functions between parts of, [>]–[>], [>]–[>], [>]

      and equipotentiality, [>]–[>]

      “wiring” of, [>]–[>] (see also Connectome)

      in childhood vs. adulthood, [>]–[>]

      and connections between regions, [>]–[>]

      and dead brains, [>]–[>]

      wires across boundaries, [>]

      See also Cortex; other brain parts

      Brain archaeology, neuroanatomy as, [>]

      Brain disorders

      epilepsy, [>], [>] (see also Epilepsy)

      infectious, [>]–[>]

      treatment of, [>]

      development of drugs for,
    [>]–[>]

      primitive methods of, [>]

      through regeneration, [>]–[>]

      and research on areas, [>]–[>]

      through rewiring, [>]–[>]

      for stroke, [>], [>], [>]–[>]

      See also Mental disorders and disabilities; Neurodegenerative disorders

      Brain injury

      and cortical area acquiring new function, [>]

      denial of by victim, [>]

      in identifying cortical areas, [>]–[>]

      from oxygen deprivation, [>]

      recovery from quicker in earlier time of life, [>]

      regeneration as treatment for, [>]–[>]

      and regional connections, [>]–[>]

      and regions affected, [>]

      rewiring facilitated by, [>], [>]

      in stroke, [>]–[>]

      symptoms of, [>]

      Brain of monkey, map of, [>], [>]

      Brain Preservation Prize, [>]

      Brain simulation, [>]–[>]

      atom-by-atom, [>]

      and change, [>]

      connectome as basis for, [>]–[>]

      and controversy over cat brain, [>]–[>]

      and extrasynaptic interactions of neurons, [>]–[>]

      and neuron-variety problem, [>]–[>]

      success criterion for, [>]–[>]

      See also Computer simulation; “Uploading”

      Brainstem, [>], [>], [>]

      “Brainstem death,” [>]–[>]

      Brain That Changes Itself, The: Stories of Personal Triumph from the Frontiers of Brain Science (Doidge), [>]

      Brain tissue, in ultramicrotome, [>]

      “Brain in a vat” scenario, [>]

      Brave New World (Huxley), [>]

      Brenner, Sydney, [>]–[>]

      Brief History of Time, A (Hawking), [>]–[>]

      Briggman, Kevin, [>]

      Broadcasting, [>]

      Broca, Paul, [>]–[>], [>]–[>], [>]

      Broca’s aphasia, [>], [>]

      Broca’s region, [>], [>], [>], [>]

      connected to Wernicke’s region, [>]–[>]

      and stroke damage, [>]

      Broca-Wernicke model of language, [>], [>], [>]

      replacement for, [>]

      Brodmann, Korbinian, [>], [>], [>], [>]

      Brodmann’s map, [>], [>], [>], [>], [>]–[>], [>]

      and brain damage, [>]

      Lashley on, [>]

      and synapse creation, [>]

      Brooks’ Law, [>]

      Byron, Lord, [>]

      Caffeine, and brain function, [>]

      Cajal, Santiago Ramón y

      and neuron classification, [>], [>], [>], [>], [>], [>], [>], [>]

      and neuron contact, [>], [>], [>], [>], [>]

      neurons drawn by, [>], [>]

      Nobel Prize to, [>]

      Calculus, simultaneous discovery of, [>]

      Campbell, Alfred, [>]

      Camus, Albert, [>]–[>]

      Candide (Voltaire), [>]

      Cat brain simulation, controversy over, [>]–[>]

      CA3 region of hippocampus, [>], [>], [>], [>]

      C. elegans worm(s), [>]–[>], [>]–[>], [>], [>]

      connectome of mapped, [>]–[>], [>], [>]

      as connectome twins, [>]–[>]

      map of nervous system (connectome) of, [>], [>], [>]

      neuron types in, [>]–[>]

      “reduced” connectome of, [>]

      simulation of (and neuron models), [>]–[>]

      slice of, [>]

      types of neurons in, [>]

      Cell(s), [>]

      Bernal on future manipulation of, [>]

      ice inside as fatal, [>]

      “programmed” death of, [>]

      Cell assembly(ies), [>], [>]–[>], [>], [>], [>], [>], [>], [>]

      creation of, [>]–[>], [>], [>], [>]

      overlapping, [>]

      spiking of, [>]

      Cell body, of neuron, [>]

      Cell theory

      acceptance of, [>]

      as cornerstone of biology, [>]

      Central nervous system (CNS), [>]

      Central sulcus, [>]

      Cerebellum, [>], [>], [>]

      in musicians, [>]

      synapse in, [>]

      Cerebral cortex, [>]–[>]

      Cerebral lateralization, [>]

      Cerebrum, [>]–[>], [>]

      and brainstem death, [>]

      Chadwick, John, [>], [>]–[>]

      Change

      from brain rewiring, [>]–[>]

      question of possibility of, [>]–[>]

      See also Learning

      Changeux, Jean-Pierre, [>]

      Channelopathy, [>]

      Chemical message

      by hormones, [>]

      between human beings, [>]–[>]

     


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