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    The Forgetting

    Page 22
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      Quétel, Claude. The History of Syphilis. Translated by Judith Braddock and Brian Pike. Baltimore: Johns Hopkins University Press, 1992.

      Rosenberg, Charles E., and Janet Golden, eds. Framing Disease: Studies in Cultural History. New Brunswick, N.J.: Rutgers University Press, 1992.

      Shorter, Edward. A History of Psychiatry: From the Era of the Asylum to the Age of Prozac. New York: John Wiley & Sons, 1997.

      Temkin, Oswei. The Double Face of Janus and Other Essays in the History of Medicine. Baltimore: Johns Hopkins University Press, 1977.

      Shift from “Senility” to “Alzheimer’s Disease”

      Cecil, Russell L., and Robert F. Loeb. A Textbook of Medicine. Philadelphia: W.B. Saunders, 1955.

      Dillman, Rob. Alzheimer’s Disease: The Concept of Disease and the Construction of Medical Knowledge. Amsterdam: Thesis Publishers, 1990.

      Fox, Patrick. “From Senility to Alzheimer’s Disease: The Rise of the Alzheimer’s Disease Movement.” Milbank Quarterly 67, Issue 1 (1989).

      HISTNEUR-L, The History of Neuroscience Internet Forum: http:www.melsch.ucla.edu/sam/bri/archives/histneur.htm

      Neumann, Meta A., and Robert Cohn. “Incidence of Alzheimer’s Disease in a Large Mental Hospital.” Archives of Neurology and Psychiatry 69 (May 1953).

      White, Lon. “Alzheimer’s Disease: The Evolution of a Diagnosis.” Public Health Reports, November-December 1997.

      Alzheimer’s Caregiving

      Henderson, Cary Smith. Partial View: An Alzheimer’s Journal. Dallas: Southern Methodist University Press, 1998.

      Kuhn, Daniel. Alzheimer’s Early Stages: First Steps in Caring and Treatment. Salt Lake City: Publishers Press, 1999.

      Mace, Nancy L., and Peter V. Rabins. The 36-Hour Day. New York: Warner, 1992.

      Michaud, Paulette. Early Stages: Changing Our Views of Alzheimer’s. New York: Alzheimer’s Association, 1998.

      Murphy, Beverly Bigtree. He Used to Be Somebody. Boulder, Colo.: Gibbs Associates, 1995.

      Snyder, Lisa. Speaking Our Minds: Personal Reflections from Individuals with Alzheimer’s. New York: W.H. Freeman, 1999.

      Stephenson, Crocker. “The Vanishing Man.” Milwaukee Journal Sentinel, 27 December 1998.

      King Lear

      Bullough, Geoffrey, ed. Narrative and Dramatic Sources of Shakespeare. Vol. 8. New York: Columbia University Press, 1973.

      Bullough, Geoffrey. “King Lear and the Annesley Case: A Reconsideration.” Festchrift Rudolf Stamm. Munich: Francke Verlag Bern, 1969.

      Shakespeare, William. King Lear. Edited by Alfred Harbage. New York: Penguin Books, 1970.

      ——. King Lear. Edited by Kenneth Muir. London: Methuen & Co., 1978.

      Morris Friedell

      The essays “Introduction to Myself and My Plight,” “Incipient Dementia: A Victim’s Perspective,” “Love in the Twilight Zone,” and “The Road to Alzheimer’s” are published, among many others, on Morris’s Internet home page: http://members.aol.com/MorrisFF.

      Human Suffering

      Becker, Ernest. The Denial of Death. New York: Free Press, 1973.

      Frankl, Viktor E. Man’s Search for Meaning. New York: Washington Square Press, 1985.

      Post, Stephen G. The Moral Challenge of Alzheimer’s Disease. Baltimore: Johns Hopkins University Press, 1995.

      Sontag, Susan. Illness as Metaphor & AIDS and Its Metaphors. New York: Anchor Books, 1990.

      Alzheimer’s Disease and Science

      Baddeley, Alan D., Barbara A. Wilson, and Fraser N. Watts, eds. Handbook of Memory Disorders. New York: John Wiley & Sons, 1998.

      Braak, Heiko, and Eva Braak. “Temporal Sequence of Alzheimer’s Disease-Related Pathology.” Vol. 14. Cerebral Cortex. Edited by Peters and Morrison. New York: Kluwer Academic/Plenum Publishers, 1999.

      Clark, Cheryl. “Irony and Illness Hit Alzheimer’s Researcher.” San Diego Union-Tribune, 6 April 1995.

      Dalton, Rex. “Researchers Caught in Dispute Over Transgenic Mice Patents.” Nature, 23 March 2000.

      Duff, Karen. “Alzheimer Transgenic Mouse Models Come of Age.” Trends in Neurosciences 20, no. 7 (July 20, 1997).

      ——. “Curing Amyloidosis: Will It Work in Humans?” Trends in Neurosciences 22, no. 11 (November 1999).

      Folstein, M. F., et al. “Mini-Mental State: A Practical Method for Grading the State of Patients for the Clinician.” Journal of Psychiatric Research 12, pp. 196–198 (1975).

      Franssen, Emile H., and Barry Reisberg. “Neurologic Markers of the Progression of Alzheimer’s Disease.” International Psychogeriatrics 9, suppl. 1 (1997).

      Franssen, Emile H., et al. “Utility of Developmental Reflexes in the Differential Diagnosis and Prognosis of Incontinence in Alzheimer’s Disease.” Journal of Geriatric Psychiatry and Neurology 10 (January 1997).

      Hyman, B. T. “The Neuropathological Diagnosis of Alzheimer’s Disease: Clinical-Pathological Studies.” Neurobiology of Aging 18, no. S4 (1997).

      Iqbal, Khalid, et. al Alzheimer’s Disease and Related Disorders: Etiology, Pathogenesis and Therapeutics. New York: John Wiley & Sons, 1999.

      Itzhaki, Ruth F. “Viruses and Alzheimer’s Disease.” Science Spectra no. 14 (1998).

      Katzman, Robert, and Katherine Bick. Alzheimer’s Disease: The Changing View. New York: Academic Press, 2000.

      Khachaturian, Zaven S. “Plundered Memories.” The Sciences, July/August 1997.

      Langreth, Robert. “To Fight Alzheimer’s, Drug Firms Place Bets on an Unproven Theory.” Wall street Journal, 8 July 1999.

      Marshall, Eliot. “Allen Roses: From ‘Street Fighter’ to Corporate Insider.” Science, 15 May 1998.

      Marx, Jean. “New ‘Alzheimer’s Mouse’ Produced.” Science, 11 October 1996.

      Masters, Colin L., and Konrad Beyreuther. “Science, Medicine, and the Future: Alzheimer’s Disease.” British Medical Journal, 7 February 1998.

      National Institute on Aging. Alzheimer’s Disease: Unraveling the Mystery. October 1995. Available at www.alzheimers.org/unravel.html

      Nelson, Peter. Interview with Karen Duff, 24 May 1999. Available at www.alzforum.org/members/forums/interview/karen_duff. html

      Pollen, Daniel A Hannah’s Heirs: The Quest for the Genetic Origins of Alzheimer’s Disease. New York: Oxford University Press, 1996.

      Reisberg, Barry. Alzheimer’s Disease: The Standard Reference. New York: Free Press, 1983.

      ——, et al. “Towards a Science of Alzheimer’s Disease Management: A Model Based Upon Current Knowledge of Retrogenesis.” International Psychogeriatrics 11, no. 1 (1999).

      ——. “Retrogenesis: Clinical, Physiologic, and Pathologic Mechanisms in Brain Aging, Alzheimer’s and Other Dementing Processes.” European Archive of Psychiatry in Clinical Neurosciences 249, suppl. 3 (1999).

      Rovner, Sandy. “Aluminum Foiled.” Washington Post, 9 March 1984.

      Singer, Dorothy G., and Tracey A. Revenson. How a Child Thinks: A Piaget Primer. New York: Plume, 1978.

      Longevity

      Alexander, Brian. “Don’t Die, Stay Pretty.” Wired, January 2000.

      Anderson, Robert N. “United States Abridged Life Tables, 1996.” National Vital Statistics Reports, 24 December 1998.

      Brookmeyer, Ron, et al. “Projections of Alzheimer’s Disease in the United States and the Public Health Impact of Delaying Disease Onset.” American Journal of Public Health, September 1998.

      Eckholm, Erik. “An Aging Nation Grapples with Care for Old and Ill.” New York Times, 27 March 1990. (Note: This is the first of four articles in the series: “Care of the Elderly; Private Burdens, Public Choices.”)

      Kirkland, Richard I. “Why We Will Live Longer … and What It Will Mean.” Fortune, 21 February 1994.

      Kristof, Nicholas D. “Aging World, New Wrinkles.” New York Times, 22 September 1996.

      Moody, Harry R. “Four Scenarios for an Aging Society.” The Hastings Center Report 24, no. 5 (September 1994).

      Olshansky, S. Jay, Bruce A. Carnes, and Christine K. Cassel. “The Aging of the Human Species.” Scientific American, Apri
    l 1993.

      Olshansky, S. Jay, Bruce A. Carnes, and Douglas Grahn. “Confronting the Boundaries of Human Longevity.” American Scientist, 11 January 1998.

      Population Institute. “1998 World Population Overview and Outlook 1999.” December 30, 1998. Available at http://www.populationinstitute.org/overview98.html

      Rice, Dorothy P., et al. “The Economic Burden of Alzheimer’s Disease Care.” Health Affairs, Summer 1993.

      U.S. Census Bureau. Sixty-Five Plus in the United States. May 1995.

      ——. “Estimated Number of People with Alzheimer’s Now and Projections for 2025 (Broken Down by State).” Available at www.census.gov/population/www/projections/pp147.html

      West, Maureen. “Turning Back Time.” Denver Rocky Mountain News, 20 July 1999.

      Jonathan Swift

      Ehrenpreis, Irvin. The Personality of Jonathan Swift. Cambridge: Harvard University Press, 1958.

      Glendinning, Victoria. Jonathan Swift. New York: Henry Holt, 1998.

      Swift, Jonathan. Gulliver’s Travels. 1726. Reprint, Boston: Houghton Mifflin, 1960.

      ——. Prose Writings of Swift. Chosen and Arranged by Walter Lewin. London: Walter Scott, Ltd., 1896.

      Wilde, W. R. The Closing Years of Dean Swift’s Life. Dublin: Hodges and Smith, 1849.

      Willem de Kooning

      Abbe, Mary. “Portrait of the Artist as an Old Man.” (Minneapolis) Star Tribune, 4 February 1996.

      de Kooning, Willem. The Late Paintings: The 1980s. San Francisco: San Francisco Museum of Modern Art/Minneapolis: Walker Art Center, 1995.

      Espinel, Carlos Hugo. “De Kooning’s Late Colours and Forms: Dementia, Creativity, and the Healing Power of Art.” Lancet, 20 April 1996.

      Larson, Kay. “Alzheimer’s Expressionism.” Village Voice, 31 May 1994.

      Pepper, Curtis Bill. “The Indomitable De Kooning.” New York Times, 20 November 1983.

      Scaruffi, Piero. “Thinking About Thought.” Science’s Last Frontiers: Consciousness, Life and Meaning. Available at www.thymos.com/tat/consc2.html

      Mnemonics

      Yates, Frances A. The Art of Memory. Chicago: University of Chicago Press, 1966.

      Frederick Law Olmsted

      Roper, Laura Wood. FLO: A Biography of Frederick Law Olmsted. Baltimore: Johns Hopkins University Press, 1983.

      Rybczynski, Witold. A Clearing in the Distance: Frederick Law Olmsted and America in the Nineteenth Century. New York: Scribner, 1999.

      Stevenson, Elizabeth. Park Maker: A Life of Frederick Law Olmsted. New York: Macmillan, 1977.

      Soliloquies

      Page 9: Michaud, Paulette. Early Stages: Changing Our Views of Alzheimer’s. New York: Alzheimer’s Association, 1998.

      Page 27: Michaud, Paulette. Early Stages: Changing Our Views of Alzheimer’s. New York: Alzheimer’s Association, 1998.

      Page 43: Henderson, Cary Smith. Partial View: An Alzheimer’s Journal Dallas: Southern Methodist University Press, 1998.

      Page 61: Snyder, Lisa. Speaking Our Minds: Personal Reflections from Individuals with Alzheimer’s. New York: W.H. Freeman, 1999.

      Page 71: Rose, Larry. Show Me the Way to Go Home. Forest Knolls, California: Elder Books, 1995.

      Page 85: Toward, Jeffrey. Interviews with early-stage patients (unpublished). Houston: University of Texas Center on Aging, 1997.

      Page 111: Snyder, Lisa. Speaking Our Minds: Personal Reflections from Individuals with Alzheimer’s. New York: W.H. Freeman, 1999.

      Page 131: Originally posted on Alzheimer List, 1998, at http://www.adrc.wustl.edu/alzheimer

      Page 147: Originally posted on Alzheimer List, 1998.

      Page 161: Originally posted on Alzheimer List, 1998.

      Page 177: Originally posted on Alzheimer List, 1999.

      Page 191: Originally posted on Alzheimer List, 1999.

      Page 215: Originally posted on Alzheimer List, 1998.

      Page 227: Petrovski, Sue. Return Journey. Book in progress.

      Page 241: Morris Friedell, “The Loneliness of a Person with Early Alzheimer’s Disease,” published online at http://members.aol.com/MorrisFF/

      INDEX

      The pagination of this electronic edition does not match the edition from which it was created. To locate a specific passage, please use the search feature of your e-book reader’s search tools.

      Abstract Expressionism, 195–206

      abstract thinking, 36, 37, 125

      acetylcholine, 62–63

      Addison, Thomas, 80

      Addison’s disease, 80

      adrenal glands, 80

      adrenalin, 46

      agnosia, 119

      AIDS, 38, 80

      alcoholism, 38, 195–96, 197, 229

      Alcott, Bronson, 83

      Alcott, Louisa May, 217–19

      alpha rhythm, 38

      aluminum, 138–40

      Aluminum Association, 139

      Alzheimer, Alois, 12–15, 22–26, 64, 68–69, 74–84, 102, 133, 143, 162–63, 182, 245

      Alzheimer Disease Research Center, 91

      Alzheimer List (website), 91–97, 121, 223

      Alzheimer Research Forum, 63–64

      Alzheimer’s Association, 32, 209

      Alzheimer’s disease:

      aesthetic experience in, 192–206

      awareness stage of, 94–97, 103–4, 192–94

      causes of, 68–70, 73, 118–20, 137–40, 151, 155–56

      cellular ultrastructure of, 133–34, 143–46

      childlike behavior in, 121–30

      coping mechanisms for, 32–33, 114

      costs of, 5, 65, 66, 88–89

      cure for, 39, 62, 67, 97, 146, 178, 209–14, 228, 235, 243–46, 251

      death from, 4, 22, 37, 40, 62, 223–26

      as degenerative condition, 19–22, 40, 97, 112–30, 141

      diagnosis and testing of, 19–22, 31, 35–39, 94–97, 115, 116, 127–28, 192

      as disease, 74–84, 129–30, 133, 137–38, 140, 142, 152–53, 250

      early stages of, 31–33, 36, 37–42, 47, 63, 94–97, 114, 154, 231

      environmental factors in, 155–56

      identification of, 12–15, 22–26, 74–84

      immunity to, 68, 137

      incidence of, 5, 30–31, 65–67, 73–74, 132–34, 163–65

      insidious onset of, 17–22, 32–35, 67, 103, 200, 221, 250

      late stages of, 21–22, 37, 69, 119, 128, 130, 201, 216–26

      in men vs. women, 67

      middle stages of, 36–37, 39–40, 63, 103–4, 112–18, 119, 130

      name of, 78–84, 183

      neurological basis of, 21–26, 70–78, 118–20, 209–24; see also neurons

      postawareness stage of, 103–4, 113, 120, 198–99

      prevention of, 228–29

      as process, 64–65, 79–80, 221–24

      public awareness of, 136–43

      as public health problem, 5, 30–32, 65–67, 132–38, 163

      reality of, 27, 93–94, 114–16, 147

      rehabilitation in, 94–95, 247–52

      research on, see research, Alzheimer’s

      resources for, 261–64

      retrogenesis in, 117–30, 221–24

      symptoms of, 13, 19–21, 63, 115, 142

      treatment for, 39, 137, 209–14, 243–46

      vaccine for, 209–14, 243–46

      Alzheimer’s Weekly, 63

      American Association of Retired Persons (AARP), 132

      amino acids, 50

      amnesia, 46–49, 201, 218–19

      amygdala, 45–46, 118, 125

      amyloid cascade hypothesis, 152, 155

      amyloid precursor protein (APP), 144, 184, 246

      amylum, 144

      Angell, Roger, 34

      anger, 12, 13, 118, 121–22, 129–30

      animal rights, 184–85

      Annesley, Bryan, 89–90, 169–70

      Annesley, Cordell, 90, 169

      anosognosia, 120

      AN 1792, 209–14

      Antabuse, 195–96

      anterograde amnesia, 46–49, 218–19

      antibodies, 2
    09–14, 243–46

      anti-inflammatory drugs, 229

      antioxidants, 228

      anxiety, 129–30

      aphasia, 13, 41, 97, 112–13, 117, 118, 169, 221

      ApoE gene, 153, 189, 245

      Archives of Neurology and Psychiatry, 84

      Area One, 46

      Area Two, 46

      Aricept, 62–63, 246, 250

      Aristophanes, 112

      As You Like It (Shakespeare), 83

      Atlantic Monthly, 1

      auditory hallucinations, 13–14, 119

      Auguste D., 12–15, 21, 22–26, 74–75, 76, 77–78, 163

      Augustine, Saint, 45, 231–32

      Auschwitz concentration camp, 96

      autoimmune response, 213–14

      autonomy, 33

      autopsies, 22–26, 35, 139

      autotoxins, 76, 102

      axons, 124, 145

      Babinski, Joseph François Felix, 222

      Babinski sign, 222

      baby boomers, 5, 65–67, 172

      Bacon, Roger, 15

      Barney, 40, 115

      Bataan Hall, 4, 67

      beta-amyloid, 143–46, 152–53, 155–57, 184, 209–14, 243–46

      biopsies, 35

      Biser, Sam, 140

      blindness, temporary, 38

      blood-brain barrier, 139, 211–12, 244

      Bok, Edward, 217–21

      Bonetti, David, 203

      Bonhoeffer, Karl, 76

      Borchelt, David, 186

      Borges, Jorge Luis, 192

      bovine spongiform encephalopathy (“mad cow disease”), 148–50

      Boyle, John, 168, 171–72

      “Brahma” (Emerson), 2

      brain:

      autopsies of, 22–26, 72–74, 124–25

      deterioration of, 20–22, 30, 37–38, 204

      as electrochemical engine, 11–12

      evolution of, 23, 53, 56–57

      functional areas of, 21–22, 45–49

      injuries to, 38, 201, 228

      modular theory of, 45–49

      neurons of, see neurons

      nonhuman, 178–89

      pathology of, 72–84, 102, 118–20

      size of, 11, 21, 37–38, 204

      tumors of, 34–35

      ventricular theory of, 45

      weight of, 23

      “white matter” of, 124

      see also specific brain areas

      brainstem, 24, 49, 222–24

      brain waves, 38, 184

      Brickman, Irving, 28, 29, 31–32, 39, 113, 114

      Brocas area, 46

     


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